Non-Receptor Type 12 Protein Tyrosine Phosphatase

A subtype of non-receptor protein tyrosine phosphatases that is characterized by the presence of a N-terminal catalytic domain and a large C-terminal domain that is enriched in PROLINE, GLUTAMIC ACID, SERINE, and THREONINE residues (PEST sequences). The phosphatase subtype is ubiquitously expressed and implicated in the regulation of a variety of biological processes such as CELL MOVEMENT; CYTOKINESIS; focal adhesion disassembly; and LYMPHOCYTE ACTIVATION.

Also Known As:

Protein Tyrosine Phosphatase, Non-Receptor Type 12; PEP PTPase; PEP Protein Tyrosine Phosphatase; PEST-Enriched Phosphatase; PTP-PEST; PEST Enriched Phosphatase; PTPase, PEP; Phosphatase, PEST-Enriched; Protein Tyrosine Phosphatase, Non Receptor Type 12

Enzymes and Coenzymes: 1
- Enzymes: 152586
  - Hydrolases: 2166
    - Esterases: 1574
      - Phosphoric Monoester Hydrolases: 7477
        Protein Tyrosine Phosphatases: 1685
        Non-Receptor Protein Tyrosine Phosphatases: 4
        Non-Receptor Type 12 Protein Tyrosine Phosphatase: 28
Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Intracellular Signaling Peptides and Proteins: 32
    - Protein Tyrosine Phosphatases: 1685
      - Non-Receptor Protein Tyrosine Phosphatases: 4
        Non-Receptor Type 12 Protein Tyrosine Phosphatase: 28

Helen E F Palmer Selected Research

Helen E F Palmer Research Topics

Disease

Drug/Important Bio-Agent (IBA)